Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9802440 | 0.73 | GAA (0.71) | GAASMN1; SMN2OPRM1MAPTMEN1 | |
| SCHEMBL10502644 | 0.73 | GAA (0.54) | GAASMN1; SMN2OPRM1MEN1KMT2A | |
| SCHEMBL28555985 | 0.72 | OPRM1 (0.46) | GAASMN1; SMN2OPRM1MAPTMEN1 | |
| SCHEMBL19838774 | 0.72 | OPRM1 (0.43) | GAASMN1; SMN2OPRM1MAPTMEN1 | |
| SCHEMBL29354473 | 0.71 | OPRM1 (0.45) | GAASMN1; SMN2OPRM1MAPTMEN1 | |
| SCHEMBL16455156 | 0.71 | OPRM1 (0.45) | GAASMN1; SMN2OPRM1MAPTMEN1 | |
| SCHEMBL9803289 | 0.71 | OPRM1 (0.41) | GAAOPRM1MAPTMEN1HTT | |
| SCHEMBL27965829 | 0.69 | GAA (0.47) | GAASMN1; SMN2OPRM1MAPTMEN1 | |
| SCHEMBL19850659 | 0.69 | OPRM1 (0.41) | GAASMN1; SMN2OPRM1MAPTKDM4E | |
| SCHEMBL9803238 | 0.69 | HRH3 (0.39) | MAPTLMNAPOLBHTR7CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049577-A | 2-pyrrolidone substituted dihydroxy alkanoic, alkenoic and alkynoic acids, compositions and HMG-CoA reductase inhibition therewith | E. R. SQUIBB & SONS, INC. (US) | 1991-09-17 | — | — | US | disclosed |