Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9803201 | 1.00 | MMP1 (0.36) | MMP1MMP2MMP3MMP9KDM4C | |
| SCHEMBL9803199 | 0.89 | EPHX1 (0.42) | MMP2EPHX1 | |
| SCHEMBL9803202 | 0.89 | EPHX1 (0.42) | MMP2EPHX1 | |
| SCHEMBL27786770 | 0.74 | MMP1 (0.35) | MMP1MMP2MMP3MMP9KDM4C | |
| SCHEMBL4950431 | 0.72 | ALOX15 (0.36) | MMP1MMP2MMP3MMP9KDM4C | |
| SCHEMBL5693362 | 0.71 | GRIK1 (0.39) | — | |
| SCHEMBL22991290 | 0.67 | MMP1 (0.39) | MMP1MMP2MMP3MMP9KDM4C | |
| SCHEMBL7413171 | 0.67 | EPHX1 (0.48) | MMP2EPHX1 | |
| SCHEMBL7413162 | 0.67 | EPHX1 (0.48) | MMP2EPHX1 | |
| SCHEMBL583601 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0181312-B1 | PROCESS FOR PREPARATION OF SUBSTITUTED PYRIDINES | Monsanto Company (US) | 1991-04-03 | — | — | EP | disclosed |