Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10586111 | 0.98 | NQO2 (0.40) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4600735 | 0.96 | NQO2 (0.41) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL9859387 | 0.95 | NQO2 (0.38) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL10951682 | 0.81 | NQO2 (0.41) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| Trifluoromethanesulfonic Acid SCHEMBL10438998 | 0.81 | HSP90AA1 (0.41) | NQO2TUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL10583282 | 0.80 | PDE4A (0.38) | ALDH1A1HSD17B10KDM4EHPGDGAA | |
| Hydrochloric Acid SCHEMBL8498491 | 0.78 | CA1 (0.54) | ALDH1A1HPGDMEN1KMT2ACYP1A2 | |
| SCHEMBL14007403 | 0.78 | LMNA (0.31) | ALDH1A1LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL3316223 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HSD17B10KDM4EHPGDGAA | |
| SCHEMBL14556505 | 0.77 | ALDH1A1 (0.39) | NQO2TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985344-A | Radiation imaging process for forming pattern without alkali-soluble polymer underlayer and water soluble radiation-sensitive diazonium salt overlayer | HITACHI, LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4983500-A | Resolution, contrast | HITACHI, LTD. (JP) | 1991-01-08 | — | — | US | disclosed |