Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9803523 | 0.99 | OPRM1 (0.43) | OPRM1OPRL1MAPK14RXFP1NPSR1 | |
| SCHEMBL9803513 | 0.93 | MAPK14 (0.44) | OPRM1OPRL1MAPK14NPSR1ALDH1A1 | |
| SCHEMBL9803767 | 0.84 | NR2F2 (0.41) | MAPK14ALDH1A1KDM4EHTR2ACYP2D6 | |
| SCHEMBL9803095 | 0.84 | KCNH2 (0.44) | OPRM1NPSR1ALDH1A1TDP1USP2 | |
| SCHEMBL30357949 | 0.83 | GPBAR1 (0.42) | OPRM1OPRL1MAPK14ALDH1A1GPBAR1 | |
| Oxalic Acid SCHEMBL9803157 | 0.82 | KDM4E (0.47) | OPRM1NPSR1ALDH1A1TDP1USP2 | |
| SCHEMBL9803091 | 0.81 | KDM4E (0.46) | MAPK14TDP1KDM4EADRB1 | |
| SCHEMBL9803763 | 0.81 | KDM4E (0.45) | MAPK14ALDH1A1KDM4E | |
| Oxalic Acid SCHEMBL9803165 | 0.79 | KDM4E (0.49) | MAPK14ALDH1A1TDP1KDM4EADRB1 | |
| SCHEMBL9803408 | 0.79 | KDM4E (0.43) | ALDH1A1KDM4EHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075325-A | Cardiovascular disorders | SYNTHELABO (FR) | 1991-12-24 | — | — | US | disclosed |
| US-5001159-A | Hypotensive, antiulcer, antiischemic agents; migraines, asthma epilepsy, anticoagulants; cardiovasculat disorders | SYNTHELABO (FR) | 1991-03-19 | — | — | US | disclosed |