Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8151669 | 0.89 | KMT2A (0.41) | ACHECES2CES1CYP3A4CA1 | |
| 1,3-Dimethoxybenzene SCHEMBL8163650 | 0.82 | ACHE (0.54) | ACHECES2CES1CYP3A4CA1 | |
| SCHEMBL2092734 | 0.81 | ALDH1A1 (0.58) | CYP3A4CA1CA2CA7CA9 | |
| 1,3-Dimethoxybenzene SCHEMBL9350 | 0.81 | ACHE (0.70) | ACHECES2CES1CYP3A4CA1 | |
| 1,3-Dimethoxybenzene SCHEMBL901285 | 0.81 | ACHE (0.70) | ACHECES2CES1CYP3A4CA1 | |
| 1,3-Dimethoxybenzene SCHEMBL27703685 | 0.79 | ACHE (0.61) | ACHECES2CES1CYP3A4CA1 | |
| SCHEMBL98118 | 0.78 | ACHE (0.56) | ACHEALDH1A1LMNAKMT2A | |
| SCHEMBL11849487 | 0.78 | ACHE (0.50) | ACHECES2CES1CYP3A4CA1 | |
| 1,3-Dimethoxybenzene SCHEMBL7860661 | 0.78 | ACHE (0.67) | ACHECES2CES1CYP3A4CA1 | |
| 1,3-Dimethoxybenzene SCHEMBL28542304 | 0.78 | ACHE (0.67) | ACHECES2CES1CYP3A4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739062-B2 | Methods for 1,4-diazo N-heterocycle synthesis | PURDUE RESEARCH FOUNDATION (US) | 2023-08-29 | — | — | US | claimed |
| US-20210009533-A1 | New Methods for 1,4-Diazo N-Heterocycle Synthesis | PURDUE RESEARCH FOUNDATION (US) | 2021-01-14 | — | — | US | claimed |
| US-10800745-B2 | Methods for 1,4-diazo n-heterocycle synthesis | PURDUE RESEARCH FOUNDATION (US) | 2020-10-13 | — | — | US | claimed |
| US-20190055205-A1 | New Methods for 1,4-Diazo N-Heterocycle Synthesis | PURDUE RESEARCH FOUNDATION (US) | 2019-02-21 | — | — | US | claimed |
| US-11739062-B2 | Methods for 1,4-diazo N-heterocycle synthesis | PURDUE RESEARCH FOUNDATION (US) | 2023-08-29 | — | — | US | disclosed |
| US-20210009533-A1 | New Methods for 1,4-Diazo N-Heterocycle Synthesis | PURDUE RESEARCH FOUNDATION (US) | 2021-01-14 | — | — | US | disclosed |
| US-10800745-B2 | Methods for 1,4-diazo n-heterocycle synthesis | PURDUE RESEARCH FOUNDATION (US) | 2020-10-13 | — | — | US | disclosed |
| US-20190055205-A1 | New Methods for 1,4-Diazo N-Heterocycle Synthesis | PURDUE RESEARCH FOUNDATION (US) | 2019-02-21 | — | — | US | disclosed |
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| EP-2570418-A2 | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-20 | — | — | EP | disclosed |
| US-8362252-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-29 | — | — | US | disclosed |
| EP-1555267-B1 | 2,3-DIHYDRO-6-NITROIMIDAZO[2,1-b]OXAZOLES | OTSUKA PHARMA CO LTD (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-4942141-A | Infrared absorbing squarylium dyes for dye-donor element used in laser-induced thermal dye transfer | EASTMAN KODAK COMPANY (US) | 1990-07-17 | — | — | US | disclosed |
| US-4912083-A | Dye containing azo group and morpholine and phenyl rings | EASTMAN KODAK COMPANY (US) | 1990-03-27 | — | — | US | disclosed |
| US-4864021-A | ANTICARCINOGENIC AGENTS, ANTITUMOR AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0323441-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |
| EP-0302441-A2 | Bis-styryl compounds | BASF Aktiengesellschaft (DE) | 1989-02-08 | — | — | EP | disclosed |
| EP-0180897-A2 | 5-Fluorouracil derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-14 | — | — | EP | disclosed |
| EP-0180188-A2 | A composition for increasing the anti-cancer activity of an anti-cancer compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-05-07 | — | — | EP | disclosed |
| US-4259350-A | PROTECTING DEGRADABLE ORGANIC MATERIAL FROM FUNGAL OR INSECT ATTACK | SANKYO COMPANY LIMITED (JP) | 1981-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10800745-B2 | Methods for 1,4-diazo n-heterocycle synthesis | AOC1, NDC1, DDO | ACHE 2159/4885CES2 1638/4885CES1 3184/4885 |
| US-20190055205-A1 | New Methods for 1,4-Diazo N-Heterocycle Synthesis | NDC1, DDO, AOC1 | ACHE 2966/4885CES2 2055/4885CES1 3664/4885 |
| US-11739062-B2 | Methods for 1,4-diazo N-heterocycle synthesis | AOC1, NDC1, DDO | ACHE 2159/4885CES2 1638/4885CES1 3184/4885 |
| US-20210009533-A1 | New Methods for 1,4-Diazo N-Heterocycle Synthesis | NDC1, DDO, AOC1 | ACHE 2966/4885CES2 2055/4885CES1 3664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.