SCHEMBL9803702

SCHEMBL9803702

Cc1cc(C)c(NS(=O)(=O)C(F)(F)F)cc1CC(N)=O

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA2 P00918 7/20 0.37
CA1 P00915 2/20 0.37
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PTGS1 P23219 9/20 0.36
PTGS2 P35354 9/20 0.36
EPHX2 P34913 1/20 0.32
KIF11 P52732 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26217664 0.74 ALDH1A1 (0.46) CA2CA1MAPK1SMN1; SMN2PTGS1
SCHEMBL55691 0.74 MAPK1 (0.54) CA2CA1MAPK1SMN1; SMN2PTGS1
SCHEMBL8537382 0.74 MAPK1 (0.54) CA2CA1MAPK1SMN1; SMN2PTGS1
Potassium SCHEMBL29827207 0.72 MAPK1 (0.53) CA2CA1MAPK1SMN1; SMN2PTGS1
SCHEMBL10680491 0.71 GPR35 (0.41) CA2CA1MAPK1SMN1; SMN2PTGS1
SCHEMBL537896 0.70 MAPT (0.39) EPHX2
Potassium Ion SCHEMBL5933675 0.70 MAPK1 (0.40) CA2CA1MAPK1SMN1; SMN2PTGS1
SCHEMBL10532691 0.69 MAPK1 (0.37) CA2CA1MAPK1SMN1; SMN2PTGS1
SCHEMBL10628416 0.69 CA2 (0.44) CA2CA1PTGS1PTGS2
SCHEMBL10933116 0.69 ALDH1A1 (0.43) CA2CA1PTGS1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107439587-A A kind of purslane shaping agent and its application method 长沙理工大学 2017-12-08 CN claimed
CN-107439587-A A kind of purslane shaping agent and its application method 长沙理工大学 2017-12-08 CN disclosed
US-4999041-A DEFOLIANTS, COTTON FARMING BASF AKTIENGESELLSCHAFT (DE) 1991-03-12 US disclosed