SCHEMBL980378

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL979498	0.88	NR4A2 (0.56)	NR4A2KDM4EALDH1A1HPGDHSD17B10
	SCHEMBL27679944	0.87	SLC22A12 (0.50)	NR4A2KDM4EALDH1A1HPGDHSD17B10
	SCHEMBL20604768	0.82	NR4A2 (0.48)	NR4A2KDM4EALDH1A1HSD17B10TSHR
	SCHEMBL14467647	0.82	NR4A2 (0.48)	NR4A2KDM4EALDH1A1HPGDHSD17B10
	SCHEMBL979534	0.81	NR4A2 (0.47)	NR4A2KDM4EALDH1A1CNR2CNR1
	SCHEMBL980636	0.81	KDM4E (0.70)	NR4A2KDM4EALDH1A1HPGDHSD17B10
	SCHEMBL21549969	0.80	NR4A2 (0.66)	NR4A2KDM4EALDH1A1HPGDHSD17B10
	SCHEMBL35211208	0.80	NR4A2 (0.66)	NR4A2KDM4EALDH1A1HPGDHSD17B10
	SCHEMBL18284305	0.79	PDE4A (0.50)	ALDH1A1CNR2CNR1CPT1ALMNA
	SCHEMBL981518	0.79	POLB (0.50)	NR4A2KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.