Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11875836 | 0.98 | S100B (0.53) | S100BMAPTHTTLMNATERT | |
| SCHEMBL11061844 | 0.96 | S100B (0.55) | S100BMAPTHTTLMNATERT | |
| Hydrochloric Acid SCHEMBL9859101 | 0.95 | S100B (0.50) | S100BMAPTHTTLMNATERT | |
| SCHEMBL10446231 | 0.92 | S100B (0.50) | S100BMAPTHTTLMNATERT | |
| SCHEMBL10815181 | 0.92 | S100B (0.50) | S100BMAPTHTTLMNATERT | |
| SCHEMBL11875957 | 0.90 | S100B (0.49) | S100BMAPTHTTLMNATERT | |
| Hydrochloric Acid SCHEMBL11875833 | 0.84 | S100B (0.49) | S100BMAPTHTTLMNATERT | |
| Trifluoromethanesulfonic Acid SCHEMBL11061600 | 0.82 | S100B (0.42) | S100BMAPTHTTLMNATERT | |
| SCHEMBL11872313 | 0.81 | MAPT (0.40) | S100BMAPTHTTLMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL9859688 | 0.80 | MAPT (0.41) | MAPTTERTALDH1A1L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985344-A | Radiation imaging process for forming pattern without alkali-soluble polymer underlayer and water soluble radiation-sensitive diazonium salt overlayer | HITACHI, LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4983500-A | Resolution, contrast | HITACHI, LTD. (JP) | 1991-01-08 | — | — | US | disclosed |