Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20020199 | 0.79 | MEN1 (0.50) | KMT2AMEN1MAPK1ALDH1A1BRD4 | |
| SCHEMBL11032320 | 0.79 | MEN1 (0.51) | KMT2AMEN1MAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20507231 | 0.76 | MEN1 (0.50) | KMT2AMEN1MAPK1ALDH1A1BRD4 | |
| SCHEMBL10777388 | 0.76 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2SIGMAR1 | |
| SCHEMBL20020177 | 0.75 | MEN1 (0.51) | KMT2AMEN1MAPK1ALDH1A1BRD4 | |
| SCHEMBL9803998 | 0.73 | MEN1 (0.46) | KMT2AMEN1ALDH1A1NR1I2CYP3A4 | |
| SCHEMBL9804070 | 0.72 | MEN1 (0.51) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL9804036 | 0.72 | MEN1 (0.47) | KMT2AMEN1MAPK1ALDH1A1NPC1 | |
| SCHEMBL9804055 | 0.70 | MEN1 (0.42) | KMT2AMEN1ALDH1A1BRD4RAB9A | |
| SCHEMBL10770087 | 0.70 | LTA4H (0.44) | MAPK1ALDH1A1CYP3A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | claimed |
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | disclosed |