Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.38 |
| ▸ | HTR1D | P28221 | 3/20 | 0.36 |
| ▸ | HTR1B | P28222 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ACP1 | P24666 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804013 | 0.80 | NCF1 (0.40) | NCF1GRM4HTR1AHTR7KDM4E | |
| SCHEMBL9804082 | 0.74 | BDKRB2 (0.39) | NCF1HTR1DHTR1BHTR1AHTR7 | |
| SCHEMBL9804044 | 0.71 | NCF1 (0.41) | NCF1MEN1KMT2A | |
| SCHEMBL9804032 | 0.71 | RAB9A (0.45) | GAAMAPTKDM4EMEN1NPC1 | |
| SCHEMBL16248312 | 0.71 | NCF1 (0.51) | NCF1HTR1DHTR1BHTR1ARAB9A | |
| SCHEMBL9804045 | 0.70 | NCF1 (0.43) | NCF1ACP1 | |
| SCHEMBL9803998 | 0.70 | MEN1 (0.46) | NCF1KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL9804018 | 0.70 | NCF1 (0.42) | NCF1HTR1DHTR1BHTR1A | |
| SCHEMBL16453464 | 0.70 | NCF1 (0.49) | NCF1HTR1DHTR1BHTR1AKDM4E | |
| SCHEMBL3268831 | 0.70 | NCF1 (0.52) | NCF1KDM4EACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026848-A | Antirhinovirus agents | SYNPHAR LABORATORIES INCORPORATED (CA) | 1991-06-25 | — | — | US | disclosed |
| EP-0335636-A1 | Antiviral compounds | SYNPHAR LABORATORIES INC. (CA) | 1989-10-04 | — | — | EP | disclosed |