SCHEMBL9804202

SCHEMBL9804202

CO[SiH](C)c1cccc(N)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
CYP3A4 P08684 3/20 0.47
CASP1 P29466 2/20 0.44
RECQL P46063 1/20 0.44
TP53 P04637 1/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA14 Q9ULX7 1/20 0.37
MAPT P10636 3/20 0.36
MAOB P27338 1/20 0.36
MAOA P21397 1/20 0.35
CYP19A1 P11511 1/20 0.35
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 1/20 0.34
ALOX15 P16050 1/20 0.34
CASP7 P55210 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL959416 0.81 ALDH1A1 (0.48) ALDH1A1CYP3A4CASP1RECQLTP53
SCHEMBL9804221 0.81 ALDH1A1 (0.33) ALDH1A1CYP3A4
SCHEMBL27696030 0.79 CYP3A4 (0.39) ALDH1A1CYP3A4CASP1RECQLTP53
SCHEMBL9325469 0.78 CYP3A4 (0.52) ALDH1A1CYP3A4CASP1RECQLTP53
SCHEMBL28106905 0.78 CYP3A4 (0.52) ALDH1A1CYP3A4CASP1RECQLTP53
SCHEMBL288583 0.72 CA4 (0.39) ALDH1A1CA12CA1CA2CA7
Methoxymethane SCHEMBL28052251 0.71 CYP3A4 (0.75) ALDH1A1CYP3A4CASP1RECQLTP53
SCHEMBL27921331 0.71 CYP3A4 (0.44) ALDH1A1CYP3A4CASP1RECQLTP53
SCHEMBL27603672 0.69 CA12 (0.30) CA12CA1CA2CA7CA9
SCHEMBL27779283 0.68 CYP3A4 (0.46) ALDH1A1CYP3A4CASP1RECQLTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0216007-B1 PROCESS FOR PRODUCING ORGANIC SILICON-TERMINATED POLYIMIDE PRECURSOR AND POLYIMIDE HITACHI, LTD. (JP) 1991-03-13 EP claimed
US-4748228-A Process for producing organic silicon-terminated polyimide precursor and polyimide HITACHI. LTD. (JP) 1988-05-31 US claimed
EP-0216007-A2 Process for producing organic silicon-terminated polyimide precursor and polyimide HITACHI, LTD. (JP) 1987-04-01 EP claimed
EP-0216007-B1 PROCESS FOR PRODUCING ORGANIC SILICON-TERMINATED POLYIMIDE PRECURSOR AND POLYIMIDE HITACHI, LTD. (JP) 1991-03-13 EP disclosed