SCHEMBL27779283

SCHEMBL27779283

CC[SiH](CC)c1cccc(N)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.46
CASP1 P29466 2/20 0.46
RECQL P46063 1/20 0.46
TP53 P04637 1/20 0.44
ALDH1A1 P00352 6/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA14 Q9ULX7 1/20 0.38
TSHR P16473 2/20 0.38
MAOA P21397 3/20 0.38
MAOB P27338 2/20 0.38
CYP19A1 P11511 1/20 0.36
KDM4E B2RXH2 3/20 0.35
MEN1 O00255 1/20 0.35
MAPT P10636 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6114699 0.84 ACHE (0.30)
SCHEMBL9325469 0.75 CYP3A4 (0.52) CYP3A4CASP1RECQLTP53ALDH1A1
SCHEMBL28106905 0.75 CYP3A4 (0.52) CYP3A4CASP1RECQLTP53ALDH1A1
SCHEMBL1172588 0.74 CYP3A4 (0.48) CYP3A4CASP1RECQLTP53ALDH1A1
SCHEMBL27338704 0.72 MAPT (0.42) CYP3A4RECQLTP53ALDH1A1TDP1
SCHEMBL8364737 0.71 TSHR (0.44) CYP3A4CASP1RECQLTP53ALDH1A1
SCHEMBL80927 0.71 TP53 (0.41) TP53TSHRMAOAMEN1KMT2A
SCHEMBL959416 0.70 ALDH1A1 (0.48) CYP3A4CASP1RECQLTP53ALDH1A1
Fluoride SCHEMBL27660896 0.69 TP53 (0.39) TP53TSHRMAOAMAOBMEN1
Alcohol SCHEMBL21680900 0.69 CYP3A4 (0.67) CYP3A4CASP1RECQLTP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105392822-A Method of aerogel synthesis NEXOLVE CORP 2016-03-09 CN claimed
CN-107849348-A Aerogel material and its production method 气凝胶科技有限责任公司 2018-03-27 CN disclosed
CN-107709424-A Systems and methods for producing aerogel materials 气凝胶科技有限责任公司 2018-02-16 CN disclosed
CN-105392822-A Method of aerogel synthesis NEXOLVE CORP 2016-03-09 CN disclosed
CN-101629059-A Adhesive composition, adhesive sheet and slicing chip attachment film SHINETSU CHEMICAL CO 2010-01-20 CN disclosed