SCHEMBL9325469

SCHEMBL9325469

C[SiH](C)c1cccc(N)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.52
CASP1 P29466 2/20 0.52
RECQL P46063 1/20 0.52
ALDH1A1 P00352 6/20 0.43
CA12 O43570 2/20 0.42
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA9 Q16790 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA7 P43166 1/20 0.42
MAPT P10636 4/20 0.41
MAOA P21397 3/20 0.41
KDM4E B2RXH2 3/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TP53 P04637 1/20 0.39
ALOX15 P16050 1/20 0.39
CASP7 P55210 1/20 0.39
NOS1 P29475 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28106905 0.85 CYP3A4 (0.52) CYP3A4CASP1RECQLALDH1A1CA12
SCHEMBL187953 0.81 ACHE (0.35)
SCHEMBL27921331 0.78 CYP3A4 (0.44) CYP3A4CASP1RECQLALDH1A1CA12
SCHEMBL9804202 0.78 ALDH1A1 (0.47) CYP3A4CASP1RECQLALDH1A1CA12
SCHEMBL959416 0.75 ALDH1A1 (0.48) CYP3A4CASP1RECQLALDH1A1CA12
SCHEMBL27779283 0.75 CYP3A4 (0.46) CYP3A4CASP1RECQLALDH1A1CA12
SCHEMBL10028297 0.74 CYP3A4 (0.36) CYP3A4MAOAMEN1KMT2A
SCHEMBL6332350 0.72 ACHE (0.55) CYP3A4ALDH1A1TDP1MAPTTP53
Ethane SCHEMBL21408539 0.72 CYP3A4 (0.86) CYP3A4CASP1RECQLALDH1A1CA12
SCHEMBL762034 0.71 MAOA (0.48) CYP3A4CASP1RECQLALDH1A1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1252135-C Proton conductive polymer and producing method thereof, membrane therewith and fuel cell with the membrane SAMSUNG SDI CO LTD (KR) 2006-04-19 CN disclosed
CN-1490345-A Proton conductive polymer and producing method thereof, membrane therewith and fuel cell with the membrane 三星SDI株式会社 2004-04-21 CN disclosed
US-5286890-A Aromatic amine terminated silicone monomers, oligomers, and polymers therefrom HUGHES AIRCRAFT COMPANY (US) 1994-02-15 US disclosed