Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804217 | 1.00 | PARP10 (0.35) | PARP10SLC6A2SLC6A4MAPK14CETP | |
| SCHEMBL9494663 | 0.86 | PARP10 (0.36) | PARP10SLC6A2SLC6A4MAPK14SLC6A3 | |
| SCHEMBL9494665 | 0.86 | PARP10 (0.36) | PARP10SLC6A2SLC6A4MAPK14SLC6A3 | |
| SCHEMBL9495144 | 0.86 | MAPK14 (0.41) | MAPK14CETPMEN1NPC1RAB9A | |
| SCHEMBL9495139 | 0.86 | MAPK14 (0.41) | MAPK14CETPMEN1NPC1RAB9A | |
| SCHEMBL9491927 | 0.84 | PARP10 (0.34) | PARP10SLC6A2SLC6A4MAPK14SLC6A3 | |
| SCHEMBL9491929 | 0.84 | PARP10 (0.34) | PARP10SLC6A2SLC6A4MAPK14SLC6A3 | |
| SCHEMBL10466635 | 0.83 | FFAR4 (0.34) | PARP10SLC6A2SLC6A4MAPK14 | |
| SCHEMBL10466636 | 0.83 | FFAR4 (0.34) | PARP10SLC6A2SLC6A4MAPK14 | |
| SCHEMBL9804277 | 0.78 | LTA4H (0.39) | SLC6A2SLC6A4MAPK14CETPSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | claimed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |