Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 2/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 7/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804274 | 1.00 | LTA4H (0.39) | LTA4HEPHX2MAPK14CETPLPAR1 | |
| SCHEMBL9804285 | 0.86 | LTA4H (0.40) | LTA4HEPHX2MAPK14CETPLPAR1 | |
| SCHEMBL9804279 | 0.86 | LTA4H (0.40) | LTA4HEPHX2MAPK14CETPLPAR1 | |
| SCHEMBL10446228 | 0.84 | MAPK14 (0.38) | LTA4HEPHX2MAPK14CETPLPAR1 | |
| SCHEMBL9804232 | 0.78 | PARP10 (0.35) | EPHX2MAPK14CETPGRIN2BTRPV1 | |
| SCHEMBL9804217 | 0.78 | PARP10 (0.35) | EPHX2MAPK14CETPGRIN2BTRPV1 | |
| SCHEMBL10455536 | 0.77 | LTA4H (0.42) | LTA4HEPHX2MAPK14CETPSLC6A2 | |
| SCHEMBL10455537 | 0.77 | LTA4H (0.42) | LTA4HEPHX2MAPK14CETPSLC6A2 | |
| SCHEMBL9560901 | 0.76 | MAPK14 (0.39) | LTA4HEPHX2MAPK14CETPLPAR1 | |
| SCHEMBL9560896 | 0.76 | MAPK14 (0.39) | LTA4HEPHX2MAPK14CETPLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | claimed |
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |