SCHEMBL2914006

SCHEMBL2914006

OCCCc1ccc(O)c(Oc2ccccc2)c1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.56
TTR P02766 1/20 0.55
IGF1R P08069 2/20 0.51
ALOX15 P16050 2/20 0.51
LTA4H P09960 1/20 0.46
EPHX2 P34913 1/20 0.46
ALOX5 P09917 2/20 0.45
POLB P06746 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
BACE1 P56817 1/20 0.44
THRA P10827 1/20 0.44
THRB P10828 1/20 0.44
CALM1 P0DP23 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2914383 0.84 TTR (0.50) TTRIGF1RALOX15LTA4HEPHX2
SCHEMBL9804282 0.83 TTR (0.46) TTRLTA4HEPHX2POLB
SCHEMBL2914999 0.82 F2 (0.43) F2IGF1RALOX15ALOX5CALM1
SCHEMBL4525681 0.79 TTR (0.56) F2TTRKDM4ETHRATHRB
SCHEMBL18240129 0.78 LTA4H (0.66) LTA4HEPHX2ALDH1A1
SCHEMBL2914322 0.78 TNKS2 (0.48) TTRLTA4HEPHX2ALOX5POLB
SCHEMBL2914798 0.78 TNKS2 (0.63) TTRALOX5KDM4EGAAMAPT
SCHEMBL28398921 0.78 F2 (0.55) F2TTRTHRATHRB
SCHEMBL29506903 0.77 TAAR1 (0.69) TTRALOX5ALDH1A1GAACALM1
SCHEMBL200345 0.77 TAAR1 (0.69) TTRALOX5ALDH1A1GAACALM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2110370-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-09-01 EP disclosed
EP-1348686-B1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL CO (JP) 2010-03-03 EP disclosed
EP-2110370-A1 Method of producing p-hydroxyphenylalkanols Sumitomo Chemical Company, Limited (JP) 2009-10-21 EP disclosed
US-6717020-B2 HIGH YIELD REACTION OF PHENOLS AND UNSATURATED ALCOHOLS IN PRESENCE OF SUCH AS TITANIUM TETRAETHOXIDE AND SODIUM METHOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-06 US disclosed
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-16 US disclosed
EP-1348686-A1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols ADH1C, NR1H3, ADH5 F2 469/4885TTR 2223/4885IGF1R 3333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.