SCHEMBL9804289

SCHEMBL9804289

C[C@@H](Oc1ccc(-c2ncc(C(F)(F)F)cc2F)cc1O)C(=O)OC[Si](C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 6/20 0.35
KCNH2 Q12809 3/20 0.35
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
POLB P06746 2/20 0.34
PTGS2 P35354 2/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
GAA P10253 1/20 0.33
AGBL2 Q5U5Z8 1/20 0.32
SLC6A5 Q9Y345 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
PTPN1 P18031 1/20 0.32
CTSA P10619 1/20 0.32
ABCB11 O95342 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9804352 1.00 SLC6A9 (0.35) SLC6A9KCNH2MEN1KMT2APOLB
SCHEMBL10561196 0.91 PPARD (0.35) SLC6A9KCNH2MEN1KMT2APOLB
SCHEMBL10562091 0.91 PPARD (0.35) SLC6A9KCNH2MEN1KMT2APOLB
SCHEMBL10413905 0.89 PTGS2 (0.35) SLC6A9KCNH2MEN1KMT2APOLB
SCHEMBL9804353 0.86 TDP1 (0.36) MEN1KMT2ACTSA
SCHEMBL9804293 0.86 TDP1 (0.36) MEN1KMT2ACTSA
SCHEMBL9804348 0.86 ABCB11 (0.43) SLC6A9KCNH2MEN1KMT2APTGS2
SCHEMBL9804459 0.86 ABCB11 (0.43) SLC6A9KCNH2MEN1KMT2APTGS2
SCHEMBL9804260 0.85 KMT2A (0.37) SLC6A9KCNH2MEN1KMT2APTGS2
SCHEMBL10387640 0.82 MEN1 (0.48) MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0200677-B1 3-FLUOROPYRIDYL-2-OXY-PHENOXY DERIVATIVES WITH A HERBICIDAL ACTIVITY CIBA-GEIGY AG (CH) 1991-04-03 EP claimed
US-4832736-A PLANT GROWTH REGULATORS CIBA-GEIGY CORPORATION (US) 1989-05-23 US claimed
US-4832736-A PLANT GROWTH REGULATORS CIBA-GEIGY CORPORATION (US) 1989-05-23 US disclosed