Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | FABP1 | P07148 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.41 |
| ▸ | ACACA | Q13085 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804310 | 1.00 | LTA4H (0.45) | LTA4HCETPTLR4TLR2FABP1 | |
| SCHEMBL9804464 | 0.87 | LTA4H (0.42) | LTA4HCETPFABP1ACACBACACA | |
| SCHEMBL9804455 | 0.87 | LTA4H (0.42) | LTA4HCETPFABP1ACACBACACA | |
| SCHEMBL9804442 | 0.78 | LTA4H (0.47) | LTA4HCETPTLR4TLR2ACACB | |
| SCHEMBL9804446 | 0.78 | LTA4H (0.47) | LTA4HCETPTLR4TLR2ACACB | |
| SCHEMBL7931627 | 0.75 | CETP (0.49) | LTA4HCETPFFAR1 | |
| SCHEMBL9804659 | 0.73 | LTA4H (0.49) | LTA4HCETPACACBACACAL3MBTL1 | |
| SCHEMBL9561406 | 0.73 | FFAR1 (0.51) | LTA4HCETPACACBACACAFFAR1 | |
| SCHEMBL409247 | 0.73 | FFAR1 (0.51) | LTA4HCETPACACBACACAFFAR1 | |
| SCHEMBL9561389 | 0.73 | LTA4H (0.48) | LTA4HCETPACACBACACAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |