Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | EPOR | P19235 | 6/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804446 | 1.00 | LTA4H (0.47) | LTA4HEPORRELAALOX5PTGS1 | |
| SCHEMBL9804433 | 0.85 | RELA (0.40) | LTA4HRELAPTGS2KDM4ECETP | |
| SCHEMBL9804436 | 0.85 | RELA (0.40) | LTA4HRELAPTGS2KDM4ECETP | |
| SCHEMBL9804535 | 0.82 | LTA4H (0.41) | LTA4HRELAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9804272 | 0.78 | LTA4H (0.42) | LTA4HRELASMN1; SMN2CETPLCK | |
| SCHEMBL9804305 | 0.78 | LTA4H (0.45) | LTA4HALDH1A1SMN1; SMN2CETPFFAR1 | |
| SCHEMBL9804310 | 0.78 | LTA4H (0.45) | LTA4HALDH1A1SMN1; SMN2CETPFFAR1 | |
| SCHEMBL9804455 | 0.76 | LTA4H (0.42) | LTA4HKDM4EALDH1A1SMN1; SMN2CETP | |
| SCHEMBL9804464 | 0.76 | LTA4H (0.42) | LTA4HKDM4EALDH1A1SMN1; SMN2CETP | |
| SCHEMBL9804659 | 0.75 | LTA4H (0.49) | LTA4HALOX5PTGS1ALDH1A1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |
| EP-0224078-A1 | Thienyl sulfonyl guanidine derivatives | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |