SCHEMBL9804422

SCHEMBL9804422

CCOc1cc(Cc2ccccc2)c(O)c(Cc2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.48
BCL2L1 Q07817 1/20 0.48
PTPN1 P18031 2/20 0.45
PTPN2 P17706 1/20 0.45
PTPN6 P29350 1/20 0.45
ALOX5 P09917 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9804677 0.85 LTA4H (0.49) BCL2BCL2L1ALOX5
SCHEMBL9804727 0.82 LTA4H (0.55) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL10870528 0.78 BCL2 (0.55) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL9804445 0.78 BCL2 (0.47) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL10906425 0.78 PTPN1 (0.47) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL10905105 0.77 BCL2 (0.50) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL670158 0.76 BCL2 (0.57) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL25329709 0.75 GABRA1 (0.44)
SCHEMBL9174306 0.75 PTPN1 (0.70) BCL2BCL2L1PTPN1PTPN2PTPN6
SCHEMBL9804555 0.75 PTPN1 (0.70) BCL2BCL2L1PTPN1PTPN2PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0186255-B1 PROCESS FOR PREPARING BENZYL SUBSTITUTED PHENOLS, DIBENZYLPHENOLIC COMPOUNDS, AND THE ANTIOXIDANT USE OF SUCH PHENOLS ETHYL CORPORATION (US) 1991-04-10 EP claimed
EP-0186255-A2 Process for preparing benzyl substituted phenols, dibenzylphenolic compounds, and the antioxidant use of such phenols ETHYL CORPORATION (US) 1986-07-02 EP claimed
EP-0186255-B1 PROCESS FOR PREPARING BENZYL SUBSTITUTED PHENOLS, DIBENZYLPHENOLIC COMPOUNDS, AND THE ANTIOXIDANT USE OF SUCH PHENOLS ETHYL CORPORATION (US) 1991-04-10 EP disclosed
EP-0186255-A2 Process for preparing benzyl substituted phenols, dibenzylphenolic compounds, and the antioxidant use of such phenols ETHYL CORPORATION (US) 1986-07-02 EP disclosed