Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 5/20 | 0.48 |
| ▸ | NMT2 | O60551 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806456 | 0.87 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL4910987 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL8323632 | 0.73 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL10575357 | 0.72 | ALDH1A1 (0.47) | NMT1NMT2SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL8325193 | 0.71 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL17331499 | 0.70 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL9619519 | 0.70 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL10574456 | 0.69 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL2970846 | 0.69 | MAPK1 (0.48) | SMN1; SMN2ALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL343728 | 0.69 | PSEN1 (0.46) | SMN1; SMN2ALDH1A1MAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3099079-A | — | — | None | — | — | JP | disclosed |
| JP-H0399079-A | INDOLIZINE DERIVATIVE | KISSEI PHARMACEUT CO LTD | 1991-04-24 | — | — | JP | disclosed |