Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804552 | 0.98 | BCL2 (0.47) | BCL2BCL2L1PTPN1PTPN2PTPN6 | |
| SCHEMBL9249706 | 0.87 | PTPN1 (0.59) | BCL2BCL2L1PTPN1PTPN2PTPN6 | |
| SCHEMBL4054377 | 0.87 | ESR2 (0.44) | ACMSD | |
| SCHEMBL22103998 | 0.84 | MEN1 (0.51) | BCL2BCL2L1ALOX5KMOACMSD | |
| SCHEMBL22103975 | 0.84 | MEN1 (0.51) | BCL2BCL2L1ALOX5KMOACMSD | |
| SCHEMBL9445279 | 0.83 | CNR2 (0.39) | KMOACMSD | |
| SCHEMBL12161247 | 0.81 | NUDT1 (0.41) | KMOACMSD | |
| SCHEMBL8155478 | 0.80 | HSPA5 (0.40) | — | |
| SCHEMBL8153644 | 0.80 | AMY1A (0.42) | — | |
| SCHEMBL18544650 | 0.79 | CYP2C9 (0.43) | KMOACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186255-B1 | PROCESS FOR PREPARING BENZYL SUBSTITUTED PHENOLS, DIBENZYLPHENOLIC COMPOUNDS, AND THE ANTIOXIDANT USE OF SUCH PHENOLS | ETHYL CORPORATION (US) | 1991-04-10 | — | — | EP | disclosed |
| EP-0186255-A2 | Process for preparing benzyl substituted phenols, dibenzylphenolic compounds, and the antioxidant use of such phenols | ETHYL CORPORATION (US) | 1986-07-02 | — | — | EP | disclosed |