Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.38 |
| ▸ | ESR1 | P03372 | 6/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054377 | 0.92 | ESR2 (0.44) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL8155478 | 0.89 | HSPA5 (0.40) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL7772545 | 0.87 | SHBG (0.41) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL2385696 | 0.86 | NUDT1 (0.39) | AMY1AESR2ESR1CYP2C9CYP2C19 | |
| SCHEMBL8151074 | 0.86 | CYP26A1 (0.37) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL8154668 | 0.85 | ESR2 (0.38) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL27946352 | 0.84 | AMY1A (0.38) | AMY1AESR2ESR1CYP2C9CYP2C19 | |
| SCHEMBL27946351 | 0.83 | NUDT1 (0.51) | AMY1AESR2ESR1CYP2C9CYP3A4 | |
| SCHEMBL8150655 | 0.83 | ESR2 (0.36) | ESR2ESR1CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL4058592 | 0.82 | AMY1A (0.58) | AMY1AESR2ESR1CYP2C9CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127087-A | COMPOSITION COMPRISING ALKALI-SOLUBLE RESIN, SPECIFIED QUINONEDIAZIDE COMPOUND | TOKYO OHKA KOGYO CO., LTD. (JP) | 2000-10-03 | — | — | US | disclosed |
| US-6106994-A | ESTERIFYING A POLYPHENOL COMPOUND AND NAPHTHOQUINONE-1,2-DIAZIDESULFONYL HALIDE IN THE PRESENCE OF FOR EXAMPLE MONOMETHYLDICYCLOHEXYLAMINE, AND POSITIVE PHOTOSENSITIVE COMPOSITION CONTAINS RESULTANT ESTER | TOKYO OHKA KOGYO CO., LTD. (JP) | 2000-08-22 | — | — | US | disclosed |