Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | FABP1 | P07148 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9804649 | 1.00 | CETP (0.44) | CETPLTA4HFFAR1FFAR4MAPK14 | |
| SCHEMBL9804338 | 0.92 | LTA4H (0.46) | CETPLTA4HFFAR1FFAR4MAPK14 | |
| SCHEMBL9804345 | 0.92 | LTA4H (0.46) | CETPLTA4HFFAR1FFAR4MAPK14 | |
| SCHEMBL9804448 | 0.92 | LTA4H (0.46) | CETPLTA4HFFAR1FFAR4MAPK14 | |
| SCHEMBL9804325 | 0.81 | KDM4E (0.48) | CETPLTA4HMAPK14SMN1; SMN2NPC1 | |
| SCHEMBL9804320 | 0.81 | KDM4E (0.48) | CETPLTA4HMAPK14SMN1; SMN2NPC1 | |
| SCHEMBL7932271 | 0.80 | AKR1C3 (0.42) | CETPFFAR1FFAR4MAPK14LMNA | |
| SCHEMBL7932267 | 0.80 | AKR1C3 (0.42) | CETPFFAR1FFAR4MAPK14LMNA | |
| SCHEMBL9804245 | 0.79 | CETP (0.42) | CETPLTA4HFFAR1FFAR4MAPK14 | |
| SCHEMBL9804247 | 0.79 | CETP (0.42) | CETPLTA4HFFAR1FFAR4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240121-B1 | DIPHENYL ETHER DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-04-17 | — | — | EP | disclosed |
| EP-0390228-A2 | Chemical intermediates | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-10-03 | — | — | EP | disclosed |
| US-4791139-A | Diphenyl ether derivatives and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-12-13 | — | — | US | disclosed |
| EP-0240121-A2 | Diphenyl ether derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-10-07 | — | — | EP | disclosed |