Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220074 | 0.80 | MAPT (0.47) | ALDH1A1CYP2A6MAPTCHRNA7WDR5 | |
| SCHEMBL28539048 | 0.78 | PPARA (0.45) | ALDH1A1CYP2A6MAPTCA1CA2 | |
| SCHEMBL30056405 | 0.78 | MAPT (0.45) | ALDH1A1CYP2A6MAPTCHRNA7WDR5 | |
| SCHEMBL7469958 | 0.78 | MAPT (0.45) | ALDH1A1CYP2A6MAPTCHRNA7WDR5 | |
| SCHEMBL23664134 | 0.76 | ACHE (0.44) | ALDH1A1MAPTCA1CA2CA9 | |
| SCHEMBL4323037 | 0.76 | CYP2A6 (0.38) | ALDH1A1CYP2A6MAPTCA1CA2 | |
| Bromide SCHEMBL28835122 | 0.76 | MAPT (0.44) | ALDH1A1CYP2A6MAPTCHRNA7WDR5 | |
| SCHEMBL4320295 | 0.76 | CYP2A6 (0.38) | ALDH1A1CYP2A6MAPTCA1CA2 | |
| SCHEMBL1230294 | 0.76 | CYP2A6 (0.38) | ALDH1A1CYP2A6MAPTCA1CA2 | |
| Bromide SCHEMBL28835121 | 0.76 | MAPT (0.44) | ALDH1A1CYP2A6MAPTCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3924336-A1 | SUBSTITUTED BICYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS | Bristol-Myers Squibb Company (US) | 2021-12-22 | — | — | EP | disclosed |
| CN-113710656-A | Substituted bicyclic compounds as farnesoid X receptor modulators | 百时美施贵宝公司 | 2021-11-26 | — | — | CN | disclosed |
| WO-2020168143-A1 | SUBSTITUTED BICYCLIC COMPOUNDS AS FARNESOID X RECEPTOR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-08-20 | — | — | WO | disclosed |
| EP-0244328-B1 | PROCESS FOR THE PREPARATION OF AROMATIC ALDEHYDES | RHONE-POULENC CHIMIE (FR) | 1991-04-10 | — | — | EP | disclosed |
| US-4990657-A | From an aromatic halide without a phase transfer agent | RHONE-POULENC CHIMIE (FR) | 1991-02-05 | — | — | US | disclosed |
| US-4978801-A | Preparation of aromatic aldehydes | RHONE-POULENC CHIMIE (FR) | 1990-12-18 | — | — | US | disclosed |
| EP-0255794-B1 | PROCESS FOR PREPARING AN AROMATIC ACID | RHONE-POULENC CHIMIE (FR) | 1990-11-07 | — | — | EP | disclosed |
| US-4942240-A | REACTION OF HYDROGEN AND CARBON MONOXIDE WITH AN AROMATIC HALIDE IN THE PRESENCE OF A NOBLE METAL CATALYSTS | RHONE-POULENC CHIMIE (FR) | 1990-07-17 | — | — | US | disclosed |
| EP-0244329-A2 | Process for the preparation of aromatic aldehydes | RHONE-POULENC CHIMIE (FR) | 1987-11-04 | — | — | EP | disclosed |
| EP-0244328-A2 | Process for the preparation of aromatic aldehydes | RHONE-POULENC CHIMIE (FR) | 1987-11-04 | — | — | EP | disclosed |