Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469958 | 0.97 | MAPT (0.45) | MAPTEPHX2GPR3CHRNA7CYP2A6 | |
| SCHEMBL30056405 | 0.97 | MAPT (0.45) | MAPTEPHX2GPR3CHRNA7CYP2A6 | |
| Bromide SCHEMBL28835122 | 0.95 | MAPT (0.44) | MAPTEPHX2GPR3CHRNA7CYP2A6 | |
| Bromide SCHEMBL28835121 | 0.95 | MAPT (0.44) | MAPTEPHX2GPR3CHRNA7CYP2A6 | |
| SCHEMBL4150750 | 0.93 | KIF11 (0.49) | MAPTEPHX2KIF11NISCHALDH1A1 | |
| SCHEMBL1393658 | 0.93 | MAPT (0.52) | MAPTEPHX2GPR3CHRNA7KIF11 | |
| SCHEMBL17281262 | 0.87 | GLB1 (0.47) | MAPTEPHX2GPR3CHRNA7PDE2A | |
| SCHEMBL4617903 | 0.87 | KIF11 (0.45) | MAPTEPHX2CHRNA7KIF11WDR5 | |
| SCHEMBL15207305 | 0.87 | CHRNA7 (0.53) | MAPTEPHX2GPR3CHRNA7WDR5 | |
| SCHEMBL254957 | 0.86 | MAPT (0.56) | MAPTEPHX2GPR3KIF11L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1464 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247383-A | Pharmaceutical compounds, salts thereof, formulations thereof, and methods of making and using the same | 基因技术公司 | 2023-12-19 | — | — | CN | claimed |
| CN-112105616-B | Pharmaceutical compounds, salts thereof, formulations thereof, and methods of making and using the same | 基因技术公司 | 2023-09-01 | — | — | CN | claimed |
| CN-116573994-A | Direct cross-coupling method of triazine ester and aryl bromide | 南京工业大学 | 2023-08-11 | — | — | CN | claimed |
| CN-116554009-A | Electrophilic cross-coupling reaction method of aryl sulfone or heteroaryl sulfone and aryl bromide | 南京工业大学 | 2023-08-08 | — | — | CN | claimed |
| EP-3746441-B1 | PHARMACEUTICAL COMPOUND, SALTS THEREOF, FORMULATIONS THEREOF, AND METHODS OF MAKING AND USING SAME | GENENTECH INC (US) | 2023-04-05 | — | — | EP | claimed |
| CN-113801015-B | Method for synthesizing aromatic carboxylic acid compound by using carbon dioxide | 华南理工大学 | 2022-11-18 | — | — | CN | claimed |
| CN-114957312-A | Aryl silicon compound of conjugated olefin and preparation method and application thereof | 南京工业大学 | 2022-08-30 | — | — | CN | claimed |
| CN-114853795-A | Arylboron compound of conjugated olefin and preparation method and application thereof | 南京工业大学 | 2022-08-05 | — | — | CN | claimed |
| CN-113387876-B | Nickel-catalyzed direct reduction cross-coupling method for heterocyclic phosphonium salt and aryl bromide and product | 南京工业大学 | 2022-04-15 | — | — | CN | claimed |
| CN-113801015-A | Method for synthesizing aromatic carboxylic acid compound by using carbon dioxide | 华南理工大学 | 2021-12-17 | — | — | CN | claimed |
| US-20200361933-A1 | PHARMACEUTICAL COMPOUND, SALTS THEREOF, FORMULATIONS THEREOF, AND METHODS OF MAKING AND USING SAME | GENENTECH, INC. | 2020-11-19 | — | — | US | claimed |
| CN-108059606-B | Method for preparing metaflumizone intermediate by using urea | 扬州工业职业技术学院 | 2020-03-27 | — | — | CN | claimed |
| CN-108129358-B | Clean and efficient metaflumizone synthesis process | 扬州工业职业技术学院 | 2020-03-24 | — | — | CN | claimed |
| WO-2019152863-A1 | PHARMACEUTICAL COMPOUND, SALTS THEREOF, FORMULATIONS THEREOF, AND METHODS OF MAKING AND USING SAME | GENENTECH, INC. (US) | 2019-08-08 | — | — | WO | claimed |
| CN-108129358-A | A kind of metaflumizone synthesis technology of clean and effective | 扬州工业职业技术学院 | 2018-06-08 | — | — | CN | claimed |
| CN-108059606-A | A kind of method that metaflumizone intermediate is prepared using urea | 扬州工业职业技术学院 | 2018-05-22 | — | — | CN | claimed |
| CN-104087308-B | A kind of trifluoromethoxy end substituted diaryl second alkynes liquid crystal compounds and synthetic method thereof | XI'AN INST. OF MODERN CHEMISTRY (CN) | 2015-12-09 | — | — | CN | claimed |
| CN-104087308-A | Trifluoromethoxy terminal-substituent diaryl acetylene liquid crystal compounds and synthetic method thereof | XIAN MODERN CHEMISTRY RES INST | 2014-10-08 | — | — | CN | claimed |
| US-6462242-B1 | BY FORMYLATION OF ARYL BROMIDES TO FORM BENZALDEHYDES AND REDUCTION OF THE LATTER USING A FORMATE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | claimed |
| EP-1059280-A2 | Process for the preparation of benzyl alcohols and their use | BAYER AG (DE) | 2000-12-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200361933-A1 | PHARMACEUTICAL COMPOUND, SALTS THEREOF, FORMULATIONS THEREOF, AND METHODS OF MAKING AND USING SAME | SLC10A1, SLC5A6, SLC26A4 | MAPT 862/4885EPHX2 1556/4885GPR3 3659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.