SCHEMBL9806315

SCHEMBL9806315

C=C(c1ccccc1)c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
PLA2G10 O15496 1/20 0.55
PLA2G2A P14555 1/20 0.55
CALM1 P0DP23 1/20 0.55
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
IDH1 O75874 1/20 0.47
PRSS1 P07477 1/20 0.46
PRSS2 P07478 1/20 0.46
PRSS3 P35030 1/20 0.46
SRD5A2 P31213 1/20 0.44
SLC22A2 O15244 1/20 0.44
LTA4H P09960 1/20 0.43
MAPT P10636 1/20 0.42
HTT P42858 1/20 0.42
GFER P55789 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GPR55 Q9Y2T6 1/20 0.42
CES2 O00748 1/20 0.41
CES1 P23141 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9476133 0.91 LMNA (0.52) LMNAPLA2G10PLA2G2ACALM1KMT2A
SCHEMBL9806296 0.88 LMNA (0.53) LMNAPLA2G10PLA2G2ACALM1KMT2A
SCHEMBL9474535 0.87 LMNA (0.47) LMNAPLA2G10PLA2G2ACALM1KMT2A
SCHEMBL9806373 0.86 HDAC1 (0.52) KMT2AMEN1MAPTHTTGFER
SCHEMBL26040612 0.85 LMNA (0.50) LMNAPLA2G10PLA2G2ACALM1KMT2A
SCHEMBL12319510 0.84 LMNA (0.57) LMNAPLA2G10PLA2G2ACALM1KMT2A
SCHEMBL8733948 0.84 MEN1 (0.52) KMT2AMEN1MAPTHTTGFER
SCHEMBL894135 0.83 MEN1 (0.65) LMNAKMT2AMEN1SRD5A2MAPT
SCHEMBL3173519 0.81 CALM1 (0.60) LMNAPLA2G10PLA2G2ACALM1KMT2A
SCHEMBL24595487 0.80 MEN1 (0.48) LMNAPLA2G10PLA2G2AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4734824-A MONOOLEFIN OR DIOLEFIN HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-29 US claimed
US-4994539-A Ethylene-unsaturated aromatic copolymer NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-02-19 US disclosed
EP-0180771-B1 METHOD FOR IMPROVING IMPULSE BREAKDOWN STRENGTH OF ELECTRICALLY INSULATING MATERIALS Nippon Petrochemicals Co., Ltd. (JP) 1989-08-02 EP disclosed
US-4734824-A MONOOLEFIN OR DIOLEFIN HAVING THREE CONDENSED OR NONCONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-29 US disclosed
EP-0154993-B1 ELECTRICAL INSULATING OIL AND ELECTRICAL APPLIANCES IMPREGNATED WITH THE SAME NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1988-03-09 EP disclosed
US-4621302-A MONO-OR DIOLEFIN HAVING THREE CONDENSED OR NON-CONDENSED AROMATIC RINGS NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1986-11-04 US disclosed
EP-0180771-A1 Method for improving impulse breakdown strength of electrically insulating materials Nippon Petrochemicals Co., Ltd. (JP) 1986-05-14 EP disclosed
EP-0154993-A1 Electrical insulating oil and electrical appliances impregnated with the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1985-09-18 EP disclosed