Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.59 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.59 |
| ▸ | IDH1 | O75874 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HNF4A | P41235 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thiobenzoic Acid SCHEMBL29060734 | 0.81 | LMNA (0.55) | CALM1LMNAPLA2G10PLA2G2AIDH1 | |
| SCHEMBL9806315 | 0.81 | LMNA (0.55) | CALM1LMNAPLA2G10PLA2G2AIDH1 | |
| SCHEMBL7895911 | 0.81 | LMNA (0.55) | CALM1LMNAPLA2G10PLA2G2AIDH1 | |
| SCHEMBL4004691 | 0.81 | LMNA (0.67) | CALM1LMNAPLA2G10PLA2G2ASRD5A2 | |
| SCHEMBL8094422 | 0.81 | CALM1 (0.92) | CALM1LMNAPLA2G10PLA2G2AIDH1 | |
| Diphenylmethane SCHEMBL10394702 | 0.81 | CALM1 (0.92) | CALM1LMNAPLA2G10PLA2G2AIDH1 | |
| SCHEMBL972712 | 0.81 | CALM1 (0.92) | CALM1LMNAPLA2G10PLA2G2AIDH1 | |
| SCHEMBL14361865 | 0.78 | TP53 (0.59) | LMNACES2CES1 | |
| SCHEMBL5482345 | 0.78 | SRD5A2 (0.71) | CALM1LMNAPLA2G10PLA2G2ASRD5A2 | |
| Benzoic Acid SCHEMBL7064148 | 0.78 | SRD5A2 (0.71) | LMNAPLA2G10PLA2G2ASRD5A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105693817-B | Tripeptide compound and preparation method and application thereof | 西北大学 | 2020-06-05 | — | — | CN | disclosed |
| CN-105693817-A | Tripeptide compound and preparation method and application thereof | 西北大学 | 2016-06-22 | — | — | CN | disclosed |
| WO-2013181697-A1 | BICYCLO[6.1.0]NON-4-YNE COMPOUNDS SUITABLE FOR USE AS LINKERS IN BIOLOGICAL APPLICATIONS | THE UNIVERSITY OF MELBOURNE (AU) | 2013-12-12 | — | — | WO | disclosed |
| US-8298513-B2 | Hexatriene-β-carbonyl compound | OSAKA UNIVERSITY (JP) | 2012-10-30 | — | — | US | disclosed |
| US-20100008857-A1 | NOVEL HEXATRIENE-BETA-CARBONYL COMPOUND | OSAKA UNIVERSITY (JP) | 2010-01-14 | — | — | US | disclosed |
| CN-1198833-C | Acetyl pyrrolidone cephlosporins with basic substitutent group | BASILEA PHARMACEUTICA AG (CH) | 2005-04-27 | — | — | CN | disclosed |
| US-RE36374-E | 1,2,3-triazole and tetrazole substituted piperidine or tetrahydropyridine compounds useful as acetylcholine agonists | H. LUNDBECK, A/S (DK) | 1999-11-02 | — | — | US | disclosed |
| US-5972929-A | Quinazolinone derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0296721-B1 | HETEROCYCLIC COMPOUNDS | H. LUNDBECK A/S (DK) | 1993-06-23 | — | — | EP | disclosed |
| US-4925858-A | NERVOUS SYSTEM DISORDERS, ALZHEIMER*S DISEASE | H. LUNDBECK A/S (DK) | 1990-05-15 | — | — | US | disclosed |
| US-4866077-A | TREATMENT OF NERVOUS SYSTEM DISORDERS SUCH AS ALZHEIMER*S DISEASE | H. LUNDBECK A/S (DK) | 1989-09-12 | — | — | US | disclosed |
| EP-0296721-A2 | Heterocyclic compounds | H. LUNDBECK A/S (DK) | 1988-12-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100008857-A1 | NOVEL HEXATRIENE-BETA-CARBONYL COMPOUND | CBR1, CBR3, DCXR | CALM1 2454/4885LMNA 2666/4885PLA2G10 3873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.