Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | F7 | P08709 | 3/20 | 0.40 |
| ▸ | F3 | P13726 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987951 | 0.82 | MEN1 (0.41) | EPHX2FAAHKMT2AMEN1LMNA | |
| SCHEMBL4934443 | 0.81 | EPHX2 (0.41) | EPHX2FAAHCNR1CNR2KMT2A | |
| SCHEMBL8756382 | 0.81 | EPHX2 (0.41) | EPHX2FAAHCNR1CNR2KMT2A | |
| SCHEMBL11711810 | 0.81 | EPHX2 (0.41) | EPHX2FAAHCNR1CNR2KMT2A | |
| SCHEMBL4821584 | 0.80 | MEN1 (0.42) | EPHX2ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL8418702 | 0.80 | EPHX2 (0.44) | EPHX2FAAHCNR1CNR2ALDH1A1 | |
| SCHEMBL16284712 | 0.79 | EPHX2 (0.36) | EPHX2FAAHCNR1CNR2ALDH1A1 | |
| SCHEMBL8403328 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPTLMNAHPGDALOX15 | |
| SCHEMBL808497 | 0.76 | MEN1 (0.41) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL9801863 | 0.76 | TSHR (0.40) | ALDH1A1MAPTLMNAHPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0170048-B1 | ALIPHATIC THIOETHERS | CIBA-GEIGY AG (CH) | 1991-04-17 | — | — | EP | disclosed |
| US-4649215-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1987-03-10 | — | — | US | disclosed |
| EP-0170048-A2 | Aliphatic thioethers | CIBA-GEIGY AG (CH) | 1986-02-05 | — | — | EP | disclosed |