Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4821584 | 0.86 | MEN1 (0.42) | MEN1KMT2AL3MBTL1AOX1TSHR | |
| SCHEMBL8987951 | 0.85 | MEN1 (0.41) | MEN1KMT2AL3MBTL1NPSR1PKM | |
| SCHEMBL11534255 | 0.84 | MEN1 (0.43) | MEN1KMT2ATSHRTP53ALDH1A1 | |
| SCHEMBL8756382 | 0.83 | EPHX2 (0.41) | MEN1KMT2ATSHRTP53MAPK1 | |
| SCHEMBL4934443 | 0.83 | EPHX2 (0.41) | MEN1KMT2ATSHRTP53MAPK1 | |
| SCHEMBL11711810 | 0.83 | EPHX2 (0.41) | MEN1KMT2ATSHRTP53MAPK1 | |
| SCHEMBL7523648 | 0.81 | GAA (0.45) | MEN1KMT2AAOX1TSHRALDH1A1 | |
| SCHEMBL808442 | 0.80 | MEN1 (0.39) | MEN1KMT2AL3MBTL1AOX1TSHR | |
| SCHEMBL11769205 | 0.79 | TDP1 (0.36) | MEN1KMT2AL3MBTL1AOX1TSHR | |
| SCHEMBL3447753 | 0.79 | MAPT (0.48) | MEN1KMT2ATSHRTP53CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678115-B1 | PROCESS FOR PREPARING FUNCTIONAL GROUP-CONTAINING OLEFINIC COMPOUNDS | 3M INNOVATIVE PROPERTIES CO (US) | 2011-11-16 | — | — | EP | claimed |
| US-20110264206-A1 | Prosthetic Valve with Sealing Members and Methods of Use Thereof | MEDTRONIC, INC. (US) | 2011-10-27 | — | — | US | claimed |
| JP-2007509142-A | — | — | 2007-04-12 | — | — | JP | claimed |
| EP-1678115-A2 | PROCESS FOR PREPARING FUNCTIONAL GROUP-CONTAINING OLEFINIC COMPOUNDS | 3M Innovative Properties Company (US) | 2006-07-12 | — | — | EP | claimed |
| WO-2005042462-A2 | PROCESS FOR PREPARING FUNCTIONAL GROUP-CONTAINING OLEFINIC COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-05-12 | — | — | WO | claimed |
| US-6838576-B1 | Process for preparing functional group-containing olefinic compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-01-04 | — | — | US | claimed |
| EP-2789602-B1 | Omega-halo-2-alkynal, method for producing the same, and method for producing conjugated Z-alken-yn-yl acetate using the same | SHINETSU CHEMICAL CO (JP) | 2017-12-27 | — | — | EP | disclosed |
| US-9714271-B2 | Cyclosporine analogue molecules modified at amino acid 1 and 3 | CONTRAVIR PHARMACEUTICALS, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-9714271-B2 | Cyclosporine analogue molecules modified at amino acid 1 and 3 | CONTRAVIR PHARMACEUTICALS, INC. (US) | 2017-07-25 | — | — | US | disclosed |
| US-9550720-B2 | Method for producing an ω-halo-2-alkynal | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-01-24 | — | — | US | disclosed |
| US-20160207961-A1 | Cyclosporine Analogue Molecules Modified At Amino Acid 1 and 3 | ACHILLE LIFE SCIENCES LIMITED (GB) | 2016-07-21 | — | — | US | disclosed |
| US-20160207961-A1 | Cyclosporine Analogue Molecules Modified At Amino Acid 1 and 3 | ACHILLE LIFE SCIENCES LIMITED (GB) | 2016-07-21 | — | — | US | disclosed |
| US-9376368-B2 | Method for producing a conjugated Z-alken-yn-yl acetate | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2016-06-28 | — | — | US | disclosed |
| US-20050143599-A1 | Process for preparing monoesters | 3M INNOVATIVE PROPERTIES COMPANY | 2005-06-30 | — | — | US | disclosed |
| WO-2005042462-A2 | PROCESS FOR PREPARING FUNCTIONAL GROUP-CONTAINING OLEFINIC COMPOUNDS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-05-12 | — | — | WO | disclosed |
| US-6838576-B1 | Process for preparing functional group-containing olefinic compounds | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-01-04 | — | — | US | disclosed |
| EP-0939073-B1 | Ester of 2,2-dimethyl-cyclopropanecarboxylic acid and their use as pesticides | SUMITOMO CHEMICAL CO (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6225495-B1 | PESTICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-05-01 | — | — | US | disclosed |
| JP-2001072614-A | PRODUCTION OF OLEFIN COMPOUND | SUMITOMO CHEM CO LTD | 2001-03-21 | — | — | JP | disclosed |
| EP-0939073-A1 | Ester of 2,2-dimethyl-cyclopropanecarboxylic acid and their use as pesticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160207961-A1 | Cyclosporine Analogue Molecules Modified At Amino Acid 1 and 3 | FKBP1A, CHP1, FKBP3 | MEN1 3090/4885KMT2A 4444/4885L3MBTL1 4138/4885 |
| US-20050143599-A1 | Process for preparing monoesters | ADSL, COASY, AGPS | MEN1 613/4885KMT2A 3292/4885L3MBTL1 4751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.