Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.56 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.56 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.56 |
| ▸ | DHFR | P00374 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806532 | 0.89 | AKR1C3 (0.59) | KMT2AAKR1C3MEN1LMNACYP1A2 | |
| SCHEMBL9806495 | 0.88 | MAPT (0.46) | KMT2AAKR1C3MEN1LMNACYP1A2 | |
| SCHEMBL9806483 | 0.83 | MEN1 (0.53) | KMT2AAKR1C3MEN1LMNACYP1A2 | |
| SCHEMBL9806514 | 0.79 | AKR1C3 (0.57) | KMT2AAKR1C3MEN1LMNACYP1A2 | |
| SCHEMBL18873558 | 0.78 | AKR1C3 (0.66) | KMT2AAKR1C3MEN1LMNACYP1A2 | |
| SCHEMBL9806509 | 0.77 | MAPT (0.49) | KMT2AAKR1C3MEN1LMNACYP1A2 | |
| SCHEMBL9806498 | 0.75 | PTGS2 (0.46) | KMT2ALMNAPTGS2MAPTHPGD | |
| SCHEMBL9806504 | 0.75 | CLCN2 (0.53) | KMT2AAKR1C3MEN1LMNACYP1A2 | |
| SCHEMBL9806488 | 0.73 | CDC25B (0.49) | KMT2AAKR1C3MEN1LMNACYP1A2 | |
| Mefenamic Acid SCHEMBL29350572 | 0.72 | PTGS2 (1.00) | KMT2AAKR1C3MEN1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | claimed |