Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 2/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25C | P30307 | 1/20 | 0.39 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806505 | 0.90 | PTGS2 (0.48) | PTGS2MAPTALOX15KDM4EPOLB | |
| SCHEMBL9806495 | 0.87 | MAPT (0.46) | PTGS2MAPTALOX15KDM4EPOLB | |
| SCHEMBL9806503 | 0.84 | CDC25B (0.47) | PTGS2MAPTALOX15KDM4EPOLB | |
| SCHEMBL9806492 | 0.80 | MAPT (0.54) | PTGS2MAPTALOX15KDM4EPOLB | |
| SCHEMBL9806587 | 0.78 | MAPT (0.51) | PTGS2MAPTALOX15KDM4EPOLB | |
| SCHEMBL9806504 | 0.77 | CLCN2 (0.53) | PTGS2MAPTKMT2ALMNACDC25B | |
| SCHEMBL9806643 | 0.76 | PTGS2 (0.49) | PTGS2MAPTALOX15KDM4EPOLB | |
| SCHEMBL9806509 | 0.76 | MAPT (0.49) | PTGS2MAPTALOX15KDM4EPOLB | |
| SCHEMBL9806489 | 0.75 | KMT2A (0.56) | PTGS2MAPTKMT2ALMNAMAPK8 | |
| SCHEMBL9806516 | 0.75 | PTGS2 (0.63) | PTGS2MAPTALOX15KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | claimed |
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | disclosed |