Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 4/20 | 0.44 |
| ▸ | CDC25A | P30304 | 1/20 | 0.44 |
| ▸ | CDC25C | P30307 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806495 | 0.89 | MAPT (0.46) | MAPTALOX15KMT2AKDM4EPOLB | |
| SCHEMBL9806488 | 0.88 | CDC25B (0.49) | MAPTALOX15KMT2AKDM4EPOLB | |
| SCHEMBL9806532 | 0.87 | AKR1C3 (0.59) | MAPTKMT2AKDM4EPOLBMAPK8 | |
| SCHEMBL9806505 | 0.86 | PTGS2 (0.48) | MAPTALOX15KMT2AKDM4EPOLB | |
| SCHEMBL9806533 | 0.81 | MAPT (0.52) | MAPTALOX15KMT2AKDM4EPOLB | |
| SCHEMBL7346692 | 0.78 | PTGS2 (0.52) | MAPTKMT2APOLBLMNAPTGS2 | |
| SCHEMBL9806483 | 0.77 | MEN1 (0.53) | MAPTKMT2AKDM4EPOLBMAPK8 | |
| SCHEMBL9806503 | 0.77 | CDC25B (0.47) | MAPTALOX15KMT2AKDM4EPOLB | |
| SCHEMBL30593451 | 0.77 | PTGS2 (0.71) | MAPTALOX15KMT2AKDM4EPOLB | |
| SCHEMBL11344390 | 0.77 | PTGS2 (0.71) | MAPTALOX15KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | claimed |