Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 4/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806587 | 0.85 | MAPT (0.51) | MAPTALOX15MAPK8MAPK9MAPK10 | |
| SCHEMBL9806509 | 0.81 | MAPT (0.49) | MAPTALOX15MAPK8MAPK9MAPK10 | |
| SCHEMBL30593451 | 0.80 | PTGS2 (0.71) | MAPTALOX15KDM4EKMT2APOLB | |
| SCHEMBL11344390 | 0.80 | PTGS2 (0.71) | MAPTALOX15KDM4EKMT2APOLB | |
| SCHEMBL19065779 | 0.79 | MAPT (0.79) | MAPTALOX15KDM4EKMT2APOLB | |
| SCHEMBL9806495 | 0.78 | MAPT (0.46) | MAPTALOX15MAPK8MAPK9MAPK10 | |
| SCHEMBL13465152 | 0.77 | MT-CO2 (0.73) | MAPTALOX15KDM4EKMT2APOLB | |
| SCHEMBL30593456 | 0.77 | MT-CO2 (0.73) | MAPTALOX15KDM4EKMT2APOLB | |
| SCHEMBL9806488 | 0.77 | CDC25B (0.49) | MAPTALOX15MAPK8MAPK9MAPK10 | |
| SCHEMBL7025322 | 0.77 | MAPT (0.61) | MAPTALOX15MAPK8MAPK9MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | claimed |
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | disclosed |