Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 6/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | CDC25C | P30307 | 1/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806506 | 0.90 | CLCN2 (0.50) | CDC25BCDC25ACDC25CMETTL3PTGS2 | |
| SCHEMBL9806488 | 0.89 | CDC25B (0.49) | CDC25BCDC25ACDC25CMETTL3PTGS2 | |
| SCHEMBL9806505 | 0.88 | PTGS2 (0.48) | CDC25BCDC25ACDC25CMETTL3PTGS2 | |
| SCHEMBL9806546 | 0.86 | PTGS2 (0.60) | METTL3PTGS2MAPTKMT2ALMNA | |
| SCHEMBL9806498 | 0.84 | PTGS2 (0.46) | CDC25BCDC25ACDC25CMETTL3PTGS2 | |
| SCHEMBL9806483 | 0.79 | MEN1 (0.53) | CDC25BCDC25ACDC25CPTGS2KDM4E | |
| SCHEMBL9806492 | 0.79 | MAPT (0.54) | CDC25BCDC25ACDC25CMETTL3PTGS2 | |
| SCHEMBL9806509 | 0.77 | MAPT (0.49) | CDC25BCDC25ACDC25CPTGS2KDM4E | |
| SCHEMBL9806544 | 0.77 | CLCN2 (0.68) | METTL3PTGS2KMT2A | |
| SCHEMBL9806587 | 0.77 | MAPT (0.51) | CDC25BCDC25ACDC25CMETTL3PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | claimed |
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | disclosed |