Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9306026 | 0.98 | POLB (0.35) | POLBHSD17B10MAOAMAOBACSL1 | |
| SCHEMBL9869663 | 0.90 | MAOA (0.37) | POLBHSD17B10MAOAMAOBACSL1 | |
| SCHEMBL9806531 | 0.86 | MAOA (0.34) | MAOAMAOBACSL1MAPTNAMPT | |
| Potassium Ion SCHEMBL9306637 | 0.84 | MEN1 (0.35) | MAOAMAOBACSL1MAPTSMN1; SMN2 | |
| SCHEMBL9806586 | 0.84 | ACSL1 (0.36) | POLBHSD17B10MAOAMAOBACSL1 | |
| SCHEMBL9306535 | 0.83 | MAOA (0.34) | MAOAMAOBACSL1MAPTNAMPT | |
| SCHEMBL640834 | 0.83 | MAOA (0.42) | POLBMAOAMAOBACSL1MAPT | |
| SCHEMBL639835 | 0.83 | MAOA (0.37) | MAOAMAOBMAPT | |
| Potassium Ion SCHEMBL9849901 | 0.82 | MAOA (0.39) | POLBMAOAMAOBACSL1P2RX4 | |
| Zinc Ion SCHEMBL15157997 | 0.82 | MAOA (0.39) | POLBMAOAMAOBACSL1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5035815-A | Synergistic, antiwear | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-07-30 | — | — | US | disclosed |
| US-5034142-A | Wear resistant compositions for engines | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-07-23 | — | — | US | disclosed |