Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ACSL1 | P33121 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806522 | 0.90 | POLB (0.35) | MAOAMAOBACSL1GAAPOLB | |
| SCHEMBL9306026 | 0.90 | POLB (0.35) | MAOAMAOBACSL1GAAPOLB | |
| SCHEMBL2421075 | 0.85 | MAOA (0.39) | MAOAMAOBACSL1POLBALOX5 | |
| SCHEMBL9870868 | 0.85 | TRPA1 (0.40) | HSD17B10CYP3A4TSHRLMNATDP1 | |
| SCHEMBL9868962 | 0.84 | ACSL1 (0.39) | MAOAMAOBACSL1HSD17B10TSHR | |
| SCHEMBL2804823 | 0.84 | MAOA (0.42) | MAOAMAOBACSL1ALOX5PPARG | |
| SCHEMBL5705630 | 0.83 | MAOA (0.41) | MAOAMAOBACSL1POLBALOX5 | |
| SCHEMBL2313646 | 0.82 | MAOA (0.46) | MAOAMAOBACSL1POLBALOX5 | |
| SCHEMBL135629 | 0.81 | BID (0.43) | MAOAMAOBHSD17B10PPARGPPARA | |
| SCHEMBL6679495 | 0.81 | PTGS1 (0.44) | MAOAMAOBACSL1P2RX4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055211-A | Lubricating oil containing a mixed ligand metal complex and a metal thiophosphate | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-10-08 | — | — | US | disclosed |