Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSL1 | P33121 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9778579 | 0.98 | ACSL1 (0.36) | ACSL1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL9868962 | 0.91 | ACSL1 (0.39) | ACSL1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL9806522 | 0.84 | POLB (0.35) | ACSL1SMN1; SMN2TSHRHSD17B10MAOB | |
| SCHEMBL9806531 | 0.83 | MAOA (0.34) | ACSL1MAOBMAOAMAPTNAMPT | |
| SCHEMBL9306026 | 0.82 | POLB (0.35) | ACSL1SMN1; SMN2TSHRHSD17B10MAOB | |
| Potassium Ion SCHEMBL9306637 | 0.82 | MEN1 (0.35) | ACSL1SMN1; SMN2RAB9ANPC1HPGD | |
| SCHEMBL9869675 | 0.81 | TRPA1 (0.39) | SMN1; SMN2RAB9ANPC1TSHRMAPT | |
| SCHEMBL9306535 | 0.81 | MAOA (0.34) | ACSL1MAOBMAOAMAPTNAMPT | |
| SCHEMBL640834 | 0.81 | MAOA (0.42) | ACSL1MAOBMAOAMAPTPOLB | |
| SCHEMBL639835 | 0.81 | MAOA (0.37) | MAOBMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5035815-A | Synergistic, antiwear | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-07-30 | — | — | US | disclosed |
| US-5034142-A | Wear resistant compositions for engines | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-07-23 | — | — | US | disclosed |