Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2266172 | 0.93 | P2RX1 (0.62) | P2RX1KLKB1RAB9ANPC1ALDH1A1 | |
| Water SCHEMBL9806558 | 0.84 | KLKB1 (0.56) | KLKB1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2272830 | 0.82 | KLKB1 (0.69) | KLKB1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2272936 | 0.81 | RAB9A (0.61) | KLKB1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5383984 | 0.77 | KLKB1 (0.66) | KLKB1RAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL330323 | 0.75 | MEN1 (0.79) | P2RX1RAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2273180 | 0.74 | PYGL (0.53) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2270561 | 0.73 | LMNA (0.68) | KLKB1ALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL25348129 | 0.73 | KLKB1 (0.61) | P2RX1KLKB1RAB9ANPC1ALDH1A1 | |
| SCHEMBL28187514 | 0.73 | RAB9A (0.52) | P2RX1RAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0423163-A1 | OXIDATIVE HAIR DYES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1991-04-24 | — | — | EP | disclosed |
| WO-1990000047-A1 | OXIDATIVE HAIR DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1990-01-11 | — | — | WO | disclosed |