Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.60 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.60 |
| ▸ | CLCN2 | P51788 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | FABP2 | P12104 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806544 | 0.91 | CLCN2 (0.68) | PTGS2METTL3CLCN2MEN1MAPK1 | |
| SCHEMBL9806516 | 0.88 | PTGS2 (0.63) | PTGS2METTL3CLCN2MEN1MAPK1 | |
| SCHEMBL9806503 | 0.86 | CDC25B (0.47) | PTGS2METTL3KMT2ALMNACYP1A2 | |
| SCHEMBL9806488 | 0.80 | CDC25B (0.49) | PTGS2METTL3MEN1KMT2AAKR1B10 | |
| SCHEMBL9806602 | 0.78 | PTGS2 (0.67) | PTGS2METTL3CLCN2MEN1MAPK1 | |
| SCHEMBL9806486 | 0.77 | CLCN2 (0.73) | PTGS2METTL3CLCN2MEN1MAPK1 | |
| SCHEMBL9806506 | 0.77 | CLCN2 (0.50) | PTGS2METTL3CLCN2MEN1MAPK1 | |
| SCHEMBL7350139 | 0.76 | PTGS2 (1.00) | PTGS2METTL3CLCN2MEN1MAPK1 | |
| SCHEMBL23386249 | 0.76 | METTL3 (1.00) | PTGS2METTL3CLCN2MEN1MAPK1 | |
| SCHEMBL9806505 | 0.74 | PTGS2 (0.48) | PTGS2METTL3KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017604-A | Antiinflammatory | WARNER-LAMBERT COMPANY (US) | 1991-05-21 | — | — | US | claimed |