Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.68 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.55 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28660979 | 0.86 | LMNA (0.56) | TMPRSS4LMNAMEN1KMT2AKDM4E | |
| SCHEMBL19024609 | 0.86 | LMNA (0.56) | TMPRSS4LMNAMEN1KMT2AKDM4E | |
| SCHEMBL1096228 | 0.86 | KMT2A (0.68) | TMPRSS4LMNAMEN1KMT2AKDM4E | |
| SCHEMBL11163149 | 0.85 | P2RX1 (0.56) | TMPRSS4LMNAMEN1KMT2AKDM4E | |
| SCHEMBL25278538 | 0.84 | PTGS2 (0.55) | TMPRSS4LMNAMEN1KMT2AKDM4E | |
| SCHEMBL19024624 | 0.83 | P2RX1 (0.57) | TMPRSS4LMNAMEN1KMT2AKDM4E | |
| SCHEMBL330113 | 0.83 | TMPRSS4 (0.67) | TMPRSS4LMNAMEN1KMT2AKDM4E | |
| SCHEMBL7179608 | 0.83 | TMPRSS4 (0.67) | TMPRSS4LMNAMEN1KMT2AKDM4E | |
| SCHEMBL7197436 | 0.83 | TMPRSS4 (0.67) | TMPRSS4LMNAMEN1KMT2AKDM4E | |
| SCHEMBL6285639 | 0.83 | TMPRSS4 (0.67) | TMPRSS4LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101648919-A | 3-substituted salicylamide compound, preparation method, medicinal composition and application thereof | INST MATERIA MEDICA CAMS | 2010-02-17 | — | — | CN | disclosed |
| EP-0423163-A1 | OXIDATIVE HAIR DYES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1991-04-24 | — | — | EP | disclosed |
| WO-1990000047-A1 | OXIDATIVE HAIR DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1990-01-11 | — | — | WO | disclosed |