Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.58 |
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | CTSB | P07858 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.55 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 2/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | CASP9 | P55211 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13471246 | 0.91 | CTSL (0.58) | CTSLCTSSCTSBCA2CA5A | |
| SCHEMBL31650959 | 0.89 | CTSL (0.57) | CTSLCTSSCTSBCA2CA5A | |
| SCHEMBL26291080 | 0.89 | CTSL (0.59) | CTSLCTSSCTSBCA2CA5A | |
| SCHEMBL26291260 | 0.89 | CTSL (0.59) | CTSLCTSSCTSBCA2CA5A | |
| SCHEMBL26291085 | 0.89 | CTSL (0.59) | CTSLCTSSCTSBCA2CA5A | |
| SCHEMBL13363809 | 0.89 | CTSD (0.62) | CTSLCTSSCTSBCA2CA5A | |
| SCHEMBL11118896 | 0.88 | CTSL (0.62) | CTSLCTSSCTSBCA2CA5A | |
| SCHEMBL2119163 | 0.88 | CTSL (0.62) | CTSLCTSSCTSBCA2CA5A | |
| SCHEMBL11468880 | 0.86 | CTSL (0.58) | CTSLCTSSCTSBCA2CA5A | |
| SCHEMBL25884406 | 0.85 | CA2 (0.55) | CTSLCTSSCTSBCA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996358-A | Control, prevention rheumatic diseases | HOFFMANN-LA ROCHE INC. (US) | 1991-02-26 | — | — | US | disclosed |