Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.59 |
| ▸ | CALCRL | Q16602 | 3/20 | 0.58 |
| ▸ | NTSR2 | O95665 | 4/20 | 0.56 |
| ▸ | NTSR1 | P30989 | 4/20 | 0.56 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.56 |
| ▸ | KDM1A | O60341 | 3/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | KDM5A | P29375 | 1/20 | 0.54 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807245 | 0.96 | EPHA2 (0.61) | EPHA2NTSR2NTSR1SORT1 | |
| SCHEMBL9807306 | 0.92 | EPHA2 (0.62) | EPHA2CALCRLKDM1AMAOBKDM5A | |
| SCHEMBL9807252 | 0.92 | EPHA2 (0.62) | EPHA2CALCRLKDM1AMAOBKDM5A | |
| SCHEMBL9551316 | 0.91 | EPHA2 (0.59) | EPHA2CALCRLNTSR2NTSR1SORT1 | |
| SCHEMBL29980542 | 0.90 | EPHA2 (0.59) | EPHA2NTSR2NTSR1SORT1KDM1A | |
| SCHEMBL9807265 | 0.89 | EPHA2 (0.61) | EPHA2NTSR2NTSR1SORT1KDM1A | |
| SCHEMBL30038002 | 0.89 | NPY4R (0.59) | — | |
| SCHEMBL13807693 | 0.88 | NTSR2 (0.56) | EPHA2NTSR2NTSR1SORT1KDM1A | |
| SCHEMBL13807691 | 0.88 | EPHA2 (0.57) | EPHA2NTSR2NTSR1SORT1 | |
| SCHEMBL9807269 | 0.88 | EPHA2 (0.63) | EPHA2NTSR2NTSR1SORT1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146266-B1 | ENZYME-RESISTANT IMMUNOMODULATORY PEPTIDES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-05-22 | — | — | EP | disclosed |
| EP-0146266-A2 | Enzyme-resistant immunomodulatory peptides | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-06-26 | — | — | EP | disclosed |
| US-4505853-A | GLANDULAR DISORDERS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-03-19 | — | — | US | disclosed |