Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.63 |
| ▸ | NPY1R | P25929 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 2/20 | 0.55 |
| ▸ | NTSR1 | P30989 | 4/20 | 0.55 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.55 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | TFPI | P10646 | 6/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.52 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.52 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807252 | 0.96 | EPHA2 (0.62) | EPHA2KDM1ATFPINMUR2NMUR1 | |
| SCHEMBL9807306 | 0.96 | EPHA2 (0.62) | EPHA2KDM1ATFPINMUR2NMUR1 | |
| SCHEMBL9691456 | 0.95 | EPHA2 (0.61) | EPHA2KDM1AAGTR2AGTR1TFPI | |
| SCHEMBL9807257 | 0.94 | NTSR1 (0.62) | EPHA2NPY1RNTSR1NTSR2AGTR2 | |
| SCHEMBL9807262 | 0.94 | EPHA2 (0.61) | EPHA2NPY1RKDM1ANTSR1NTSR2 | |
| SCHEMBL9807265 | 0.93 | EPHA2 (0.61) | EPHA2NPY1RKDM1ANTSR1NTSR2 | |
| SCHEMBL9807253 | 0.93 | EPHA2 (0.58) | EPHA2NPY1RKDM1ANTSR1NTSR2 | |
| SCHEMBL9807235 | 0.93 | EPHA2 (0.64) | EPHA2NPY1RSLC6A2NMUR2NMUR1 | |
| SCHEMBL9807245 | 0.92 | EPHA2 (0.61) | EPHA2NTSR1NTSR2AGTR2AGTR1 | |
| SCHEMBL9807268 | 0.92 | KDM1A (0.57) | EPHA2KDM1ATFPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146266-B1 | ENZYME-RESISTANT IMMUNOMODULATORY PEPTIDES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-05-22 | — | — | EP | disclosed |
| EP-0146266-A2 | Enzyme-resistant immunomodulatory peptides | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-06-26 | — | — | EP | disclosed |