Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.62 |
| ▸ | KDM1A | O60341 | 3/20 | 0.58 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.55 |
| ▸ | TFPI | P10646 | 6/20 | 0.55 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.54 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.53 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | KDM5A | P29375 | 1/20 | 0.53 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807252 | 1.00 | EPHA2 (0.62) | EPHA2KDM1ACALCRLTFPIKISS1R | |
| SCHEMBL9807269 | 0.96 | EPHA2 (0.63) | EPHA2KDM1ATFPINMUR2NMUR1 | |
| SCHEMBL9807268 | 0.95 | KDM1A (0.57) | EPHA2KDM1ATFPIKISS1ROPRM1 | |
| SCHEMBL9551264 | 0.95 | EPHA2 (0.60) | EPHA2KDM1ACALCRLTFPIKISS1R | |
| SCHEMBL9807262 | 0.94 | EPHA2 (0.61) | EPHA2KDM1ATFPINMUR2NMUR1 | |
| SCHEMBL9807256 | 0.92 | EPHA2 (0.59) | EPHA2KDM1ACALCRLMAOBKDM5A | |
| SCHEMBL9691456 | 0.91 | EPHA2 (0.61) | EPHA2KDM1ACALCRLTFPIOPRM1 | |
| SCHEMBL9807257 | 0.91 | NTSR1 (0.62) | EPHA2 | |
| SCHEMBL9807265 | 0.89 | EPHA2 (0.61) | EPHA2KDM1ANMUR2NMUR1MAOB | |
| SCHEMBL9807235 | 0.89 | EPHA2 (0.64) | EPHA2NMUR2NMUR1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0146266-B1 | ENZYME-RESISTANT IMMUNOMODULATORY PEPTIDES | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-05-22 | — | — | EP | disclosed |
| EP-0146266-A2 | Enzyme-resistant immunomodulatory peptides | ORTHO PHARMACEUTICAL CORPORATION (US) | 1985-06-26 | — | — | EP | disclosed |