SCHEMBL9807268

CC(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(N)=O)C(C)C

nearest known ligand 0.57

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	KDM1A	O60341	2/20	0.57

▸	EPHA2	P29317	2/20	0.57

▸	TFPI	P10646	6/20	0.55

▸	IL23R	Q5VWK5	1/20	0.55

▸	KISS1R	Q969F8	2/20	0.54

▸	OPRM1	P35372	5/20	0.54

▸	OPRK1	P41145	5/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL9807306	0.95	EPHA2 (0.62)	KDM1AEPHA2TFPIKISS1ROPRM1
SCHEMBL9807252	0.95	EPHA2 (0.62)	KDM1AEPHA2TFPIKISS1ROPRM1
SCHEMBL9807269	0.92	EPHA2 (0.63)	KDM1AEPHA2TFPI
SCHEMBL9551264	0.90	EPHA2 (0.60)	KDM1AEPHA2TFPIKISS1ROPRM1
SCHEMBL9807253	0.90	EPHA2 (0.58)	KDM1AEPHA2OPRM1OPRK1
SCHEMBL9807262	0.89	EPHA2 (0.61)	KDM1AEPHA2TFPIIL23R
SCHEMBL31307252	0.88	EPHA2 (0.63)	KDM1AEPHA2OPRM1
SCHEMBL9807256	0.88	EPHA2 (0.59)	KDM1AEPHA2
SCHEMBL31575684	0.87	KDM1A (0.56)	KDM1AEPHA2
SCHEMBL30953195	0.86	SLC6A2 (0.61)	EPHA2IL23RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0146266-B1	ENZYME-RESISTANT IMMUNOMODULATORY PEPTIDES	ORTHO PHARMACEUTICAL CORPORATION (US)	1991-05-22	—	—	EP	disclosed
EP-0146266-A2	Enzyme-resistant immunomodulatory peptides	ORTHO PHARMACEUTICAL CORPORATION (US)	1985-06-26	—	—	EP	disclosed