Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL982312 | 0.88 | MAOB (0.39) | KIF11KCNH2 | |
| SCHEMBL980138 | 0.87 | HCRTR1 (0.35) | KIF11 | |
| SCHEMBL981265 | 0.85 | KIF11 (0.45) | KIF11 | |
| SCHEMBL980074 | 0.85 | MET (0.44) | — | |
| SCHEMBL5046577 | 0.73 | KIF11 (0.40) | KIF11KCNH2 | |
| SCHEMBL980244 | 0.72 | MAOA (0.40) | KIF11 | |
| SCHEMBL979241 | 0.72 | MET (0.40) | KIF11KCNH2 | |
| SCHEMBL28661764 | 0.67 | KIF11 (0.46) | KIF11KCNH2 | |
| SCHEMBL980246 | 0.66 | KIF11 (0.34) | KIF11KCNH2 | |
| SCHEMBL17004383 | 0.66 | MET (0.49) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875644-B2 | tyrosine kinase inhibitors, in particular Met kinase; antitumor agents;1-(Benzo-1,2,5-thiadiazol-5-ylmethylcarbonyl)-3-(2,4-dimethoxyphenyl)-4,5-dihydro-1H-pyrazole; leukemia, carcinomas | MERCK PATENT GMBH (DE) | 2011-01-25 | — | — | US | claimed |