Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5460996 | 0.91 | LMNA (0.43) | CNR2LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL15065449 | 0.91 | LMNA (0.43) | CNR2LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL10340840 | 0.91 | LMNA (0.43) | CNR2LMNAHDAC3HDAC1HDAC2 | |
| SCHEMBL15871096 | 0.89 | CYP1A2 (0.42) | CNR2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL9807501 | 0.88 | LSS (0.39) | LSSALDH1A1MEN1KMT2AHDAC1 | |
| SCHEMBL9807489 | 0.88 | LSS (0.38) | LSSALDH1A1MEN1KMT2AHDAC3 | |
| SCHEMBL8167313 | 0.85 | ALDH1A1 (0.42) | LSSCNR2LMNAALDH1A1MEN1 | |
| SCHEMBL8686089 | 0.84 | ALDH1A1 (0.44) | LSSLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL1275299 | 0.84 | EGFR (0.44) | CNR2LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL5058728 | 0.82 | INSR (0.48) | LMNAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0427815-A1 | HEMICYANINE MAIN-CHAIN POLYMERS | MERCK PATENT GmbH (DE) | 1991-05-22 | — | — | EP | disclosed |
| WO-1990013055-A1 | HEMICYANINE MAIN-CHAIN POLYMERS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-11-01 | — | — | WO | disclosed |