SCHEMBL9807772

SCHEMBL9807772

CCCCCCCCC#CN/C=C/N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN7 P35236 5/20 0.36
HMGCR P04035 5/20 0.36
RECQL P46063 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
EPHX2 P34913 3/20 0.33
SELP P16109 1/20 0.32
KCNH2 Q12809 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
ALOX12 P18054 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
MCL1 Q07820 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2394010 0.76 ADH1B (0.45) PTPN7HMGCRRECQLTDP1EPHX2
SCHEMBL2393879 0.74 ADH1B (0.41) PTPN7HMGCRRECQLTDP1EPHX2
SCHEMBL26553386 0.72 PTPN7 (0.45) PTPN7HMGCRRECQLTDP1EPHX2
SCHEMBL26553373 0.72 PTPN7 (0.45) PTPN7HMGCRRECQLTDP1EPHX2
SCHEMBL9807775 0.71 DNM1 (0.41) PTPN7HMGCREPHX2SELPMEN1
SCHEMBL5169071 0.70 PTPN7 (0.43) PTPN7HMGCRRECQLTDP1EPHX2
SCHEMBL5166979 0.70 PTPN7 (0.43) PTPN7HMGCRRECQLTDP1EPHX2
SCHEMBL5168625 0.70 PTPN7 (0.43) PTPN7HMGCRRECQLTDP1EPHX2
SCHEMBL5168617 0.70 PTPN7 (0.43) PTPN7HMGCRRECQLTDP1EPHX2
SCHEMBL5166971 0.70 PTPN7 (0.43) PTPN7HMGCRRECQLTDP1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0323163-B1 SHIFT-FEEL DURABILITY ENHANCEMENT ETHYL PETROLEUM ADDITIVES, INC. (US) 1991-05-29 EP disclosed
EP-0323163-A1 Shift-feel Durability enhancement ETHYL PETROLEUM ADDITIVES, INC. (US) 1989-07-05 EP disclosed
US-4795583-A FRICTION MODIFIER FOR AUTOMATIC TRANSMISSION FLUIDS CONTAINING AN ALIPHATIC TERTIARY AMINE, ALIPHATIC DIAMINE AND-OR N-SUBSTITUTED DIALKANOLAMINE ETHYL PETROLEUM ADDITIVES, INC. (US) 1989-01-03 US disclosed