Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.42 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.42 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808172 | 0.91 | TDP1 (0.45) | HPGDALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9808060 | 0.87 | ALDH1A1 (0.53) | HPGDALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9808064 | 0.87 | HPGD (0.53) | HPGDALDH1A1SMN1; SMN2RAB9AMAPT | |
| SCHEMBL9808250 | 0.81 | HDAC1 (0.54) | ALDH1A1SMN1; SMN2CYP2C9CYP2C19NPC1 | |
| SCHEMBL9808054 | 0.79 | HTT (0.49) | HPGDALDH1A1MAPTKMT2ALMNA | |
| SCHEMBL7846060 | 0.76 | CA2 (0.44) | HPGDALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9750261 | 0.76 | ESR1 (0.44) | — | |
| SCHEMBL9808094 | 0.76 | TEAD1 (0.53) | HPGDALDH1A1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL9808180 | 0.75 | APP (0.42) | ALDH1A1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL9808059 | 0.74 | GAA (0.40) | CYP1A2CYP3A4CYP2C9CYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |